Journal article
The absolute configuration of (2S,4S)and (2R,4R)-2-tert-butyl-4-methyl-3-(4-tolylsulfonyl)-1,3-oxazolidine-4-carbaldehyde



Publication Details
Authors:
Flock, S.; Bruhn, C.; Frauenrath, H.
Publication year:
2006
Journal:
Acta Crystallographica Section C: Crystal Structure Communications
Pages range:
O101-O103
Volume number:
62
Start page:
O101
End page:
O103
ISSN:
0108-2701

Abstract
The title enantiomorphic compounds, C16H23NO4S, have been obtained in an enantiomerically pure form by crystallization from a diastereomeric mixture either of (2S,4S)- and (2R, 4S)or of (2R, 4R)- and (2S, 4R)-2-tert-butyl-4-methyl-3-(4-tolylsulfonyl)1,3- oxazolidine-4-carbaldehyde. These mixtures were prepared by an aziridination rearrangement process starting with ( S)- or ( R)-2-tert-butyl-5-methyl-4H- 1,3- dioxine. The crystal structures indicate an envelope conformation of the oxazolidine moiety for both compounds.

Last updated on 2019-01-11 at 16:05