Aufsatz in einer Fachzeitschrift
Enantioselective synthesis of 1-(1,3-dioxolan-2-yl)-3-pentanol from 3-(1,3-dioxolan-2-yl)-propanal by catalytic ethylation



Details zur Publikation
Autor(inn)en:
Wilken, J.; Winter, M.; Stahl, I.; Martens, J.
Publikationsjahr:
2000
Zeitschrift:
Tetrahedron: Asymmetry
Seitenbereich:
1073-1075
Jahrgang/Band:
11
ISSN:
0957-4166

Zusammenfassung, Abstract
The catalytic enantioselective ethylation of 3-(1,3-dioxolan-2-yl)-propanal by diethylzinc in the presence of various beta-aminoalcohol precatalysts is presented. The enantiocontrolled alkylation step was accomplished with enantiomeric ratios of up to 86:14 and chemical yields ranging from 38 to 81% for the resulting 1-(1,3-dioxolan-2-yl)-3-pentanol. (C) 2000 Elsevier Science Ltd. All rights reserved.

Zuletzt aktualisiert 2019-01-11 um 16:04