Journal article
Guidelines and recommendations on yeast cell death nomenclature



Publication Details
Authors:
Carmona-Gutierrez, D.; Bauer, M.; Zimmermann, A.; Aguilera, A.; Austriaco, N.; Ayscough, K.; Balzan, R.; Bar-Nun, S.; Barrientos, A.; Belenky, P.; Blondel, M.; Braun, R.; Breitenbach, M.; Burhans, W.; Büttner, S.; Cavalieri, D.; Chang, M.; Cooper, K.; Corte-Real, M.; Costa, V.; Cullin, C.; Dawes, I.; Dengjel, J.; Dickman, M.; Eisenberg, T.; Fahrenkrog, B.; Fasel, N.; Frohlich, K.; Gargouri, A.; Giannattasio, S.; Goffrini, P.; Gourlay, C.; Grant, C.; Greenwood, M.; Guaragnella, N.; Heger, T.; Heinisch, J.; Herker, E.; Herrmann, J.; Hofer, S.; Jimenez-Ruiz, A.; Jungwirth, H.; Kainz, K.; Kontoyiannis, D.; Ludovico, P.; Manon, S.; Martegani, E.; Mazzoni, C.; Megeney, L.; Meisinger, C.; Nielsen, J.; Nystrom, T.; Osiewacz, H.; Outeiro, T.; Park, H.; Pendl, T.; Petranovic, D.; Picot, S.; Polcic, P.; Powers, T.; Ramsdale, M.; Rinnerthaler, M.; Rockenfeller, P.; Ruckenstuhl, C.; Schaffrath, R.; Segovia, M.; Severin, F.; Sharon, A.; Sigrist, S.; Sommer-Ruck, C.; Sousa, M.; Thevelein, J.; Thevissen, K.; Titorenko, V.; Toledano, M.; Tuite, M.; Voegtle, F.; Westermann, B.; Winderickx, J.; Wissing, S.; Woelfl, S.; Zhang, Z.; Zhao, R.; Zhou, B.; Galluzzi, L.; Kroemer, G.; Madeo, F.
Publisher:
SHARED SCIENCE PUBLISHERS OG
Publication year:
2018
Journal:
Microbial Cell
Pages range:
4-31
Volume number:
5
Issue number:
1
Start page:
4
End page:
31
Number of pages:
28
ISSN:
2311-2638

Abstract
Elucidating the biology of yeast in its full complexity has major implications for science, medicine and industry. One of the most critical processes determining yeast life and physiology is cellular demise. However, the investigation of yeast cell death is a relatively young field, and a widely accepted set of concepts and terms is still missing. Here, we propose unified criteria for the definition of accidental, regulated, and programmed forms of cell death in yeast based on a series of morphological and biochemical criteria. Specifically, we provide consensus guidelines on the differential definition of terms including apoptosis, regulated necrosis, and autophagic cell death, as we refer to additional cell death routines that are relevant for the biology of (at least some species of) yeast. As this area of investigation advances rapidly, changes and extensions to this set of recommendations will be implemented in the years to come. Nonetheless, we strongly encourage the authors, reviewers and editors of scientific articles to adopt these collective standards in order to establish an accurate framework for yeast cell death research and, ultimately, to accelerate the progress of this vibrant field of research.


Keywords
accidental cell death, apoptosis, autophagic cell death, autophagy, caspases, mitochondrial membrane permeabilization, mitotic catastrophe, model organism, necrosis, reactive oxygen species, regulated cell death, Saccharomyces cerevisiae

Last updated on 2019-25-07 at 18:57