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Biophysics

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2008	Anbazhagan, V., Vijay, N., Kleinschmidt, J.H., Marsh, D., 2008. Protein-lipid interactions with Fusobacterium nucleatum major outer membrane protein FomA: spin-label EPR and polarized infrared spectroscopy. Biochemistry 47, 8414–8423. https://doi.org/10.1021/bi800750s
2007	Qu, J., Mayer, C., Behrens, S., Holst, O., Kleinschmidt, J.H., 2007. The trimeric periplasmic chaperone Skp of Escherichia coli forms 1:1 complexes with outer membrane proteins via hydrophobic and electrostatic interactions. Journal of Molecular Biology 374, 91–105. https://doi.org/10.1016/j.jmb.2007.09.020
2006	Pocanschi, C.L., Dahmane, T., Gohon, Y., Rappaport, F., Apell, H.-J., Kleinschmidt, J.H., Popot, J.-L., 2006. Amphipathic polymers: tools to fold integral membrane proteins to their active form. Biochemistry 45, 13954–13961. https://doi.org/10.1021/bi0616706
2006	Pocanschi, C.L., Patel, G.J., Marsh, D., Kleinschmidt, J.H., 2006. Curvature elasticity and refolding of OmpA in large unilamellar vesicles. Biophysical Journal 91, 75–77. https://doi.org/10.1529/biophysj.106.091439
2006	Kleinschmidt, J.H., 2006. Folding kinetics of the outer membrane proteins OmpA and FomA into phospholipid bilayers. Chemistry and Physics of Lipids 141, 30–47. https://doi.org/10.1016/j.chemphyslip.2006.02.004
2006	Marsh, D., Shanmugavadivu, B., Kleinschmidt, J.H., 2006. Membrane elastic fluctuations and the insertion and tilt of beta-barrel proteins. Biophysical Journal 91, 227–232. https://doi.org/10.1529/biophysj.105.079004
2006	Pocanschi, C.L., Apell, H.-J., Puntervoll, P., Høgh, B., Jensen, H.B., Welte, W., Kleinschmidt, J.H., 2006. The major outer membrane protein of Fusobacterium nucleatum (FomA) folds and inserts into lipid bilayers via parallel folding pathways. Journal of Molecular Biology 355, 548–561. https://doi.org/10.1016/j.jmb.2005.10.060
2005	Mogensen, J.E., Kleinschmidt, J.H., Schmidt, M.A., Otzen, D.E., 2005. Misfolding of a bacterial autotransporter. Protein Science 14, 2814–2827. https://doi.org/10.1110/ps.051628705

Projects

2008 - 2014

Insertion and folding of integral membrane proteins into lipid bilayers - Effects of YaeT and membrane-anchored lipoproteins on membrane-protein folding