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Biochemistry (for Biologists)

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2011	Pavlidis, I., 2011. Studie über die Struktur und Funktion von Hydrolasen in nanostrukturierten Systemen.
2009	Jablonowski, D., Täubert, J.-E., Stark, M., Bär, C., Schaffrath, R., 2009. Distinct Subsets of Sit4 Holophosphatases Are Required for Inhibition of Saccharomyces cerevisiae Growth by Rapamycin and Zymocin. Eukaryotic Cell 8, 1637–1647. https://doi.org/10.1128/EC.00205-09
2009	Mehlgarten, C., Jablonowski, D., Breunig, K.D., Stark, M., Schaffrath, R., 2009. Elongator function depends on antagonistic regulation by casein kinase Hrr25 and protein phosphatase Sit4. Molecular Microbiology 73, 869–881. https://doi.org/10.1111/j.1365-2958.2009.06811.x
2009	Pfitzner, E., 2009. STAT6 and STAT1 are essential antagonistic regulators of cell survival in classical Hodgkin lymphoma cell line. Leukemia 23, 1885–1893. https://doi.org/10.1038/leu.2009.103
2008	Pfitzner, E., 2008. Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation. Breast Cancer Research and Treatment 10, R94. https://doi.org/10.1186/bcr2193
2008	Pfitzner, E., 2008. p160/SRC/NCoA coactivators form complexes via specific interaction of their PAS-B domain with the CID/AD1 domain. Nucleic Acids Research 36, 1847–1860. https://doi.org/10.1093/nar/gkn029
2008	Nandakumar, J., Schwer, B., Schaffrath, R., Shuman, S., 2008. RNA repair: An antidote to cytotoxic eukaryal RNA damage. Molecular Cell 31, 278–286. https://doi.org/10.1016/j.molcel.2008.05.019
2008	Studte, P., Zink, S., Jablonowski, D., Bär, C., von der Haar, T., Tuite, M.F., Schaffrath, R., 2008. tRNA and protein methylase complexes mediate zymocin toxicity in yeast. Molecular Microbiology 69, 1266–1277. https://doi.org/10.1111/j.1365-2958.2008.06358.x
2007	Pfitzner, E., 2007. Targeting the oligomerization domain of ETO interferes with RUNX1/ETO oncogenic activity in t(8 ; 21)-positive leukemic cells. Cancer Research 67, 2280–2289. https://doi.org/10.1158/0008-5472.CAN-06-3360
2007	Pfitzner, E., 2007. Transcription linked to recombination: a gene-internal promoter coincides with the recombination hot spot II of the human MLL gene. Oncogene 26, 1361–1371. https://doi.org/10.1038/sj.onc.1209948

Projects

03/2022 - 10/2026	GRK 2749/1_Multiscale Clocks_TP 11
01/2016 - 12/2018	Application of methyltransferases for the production of high value-added products
07/2013 - 07/2015	The Nociceptor Pain Model
04/2010 - 03/2015	Protein Binders for Characterisation of Human Proteome Function: Generation, Validation, Application
10/2009 - 01/2013	Advanced affinity tools and technologies for high throughput studies of the human proteome (AffinityProteome)
09/2009 - 05/2012	MedSys-Verbundvorhaben: Modellierung von peripheren Schmerzschaltern
05/2006 - 12/2010	Promotionskolleg Proteomics