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Biophysics

University of Kassel » Fachbereiche » Faculty of Mathematics and Natural Sciences » Institut für Biologie

URL:	http://www.uni-kassel.de/fb10/de/institute/biologie/fachgebiete/biophysik-dach.html

Address:

Heinrich-Plett-Str. 40
34130 Kassel

Persons

Prof. Dr. Jörg Η. Kleinschmidt

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Projects

12/2008 - 09/2021	Insertion and folding of beta-barrel membrane proteins into lipid bilayers - Functions of BamA (YaeT) and of membrane anchored Bam lipoproteins in membrane protein folding.
2008 - 2014	Insertion and folding of integral membrane proteins into lipid bilayers - Effects of YaeT and membrane-anchored lipoproteins on membrane-protein folding

Publications

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2022	Pocanschi, C.L., Kleinschmidt, J.H., 2022. The Thermodynamic Stability of Membrane Proteins in Micelles and Lipid Bilayers Investigated with the Ferrichrom Receptor FhuA. The Journal of Membrane Biology 255, 485–502. https://doi.org/10.1016/S0006-3495(97)78283-3
2020	Martin, C., Hering, L., Metzendorf, N., Hormann, S., Kasten, S., Fuhrmann, S., Werckenthin, A., Herberg, F.W., Stengl, M., Mayer, G., 2020. Analysis of Pigment-Dispersing Factor Neuropeptides and Their Receptor in a Velvet Worm. Frontiers in Endocrinology 11, 273. https://doi.org/10.3389/fendo.2020.00273
2020	Herwig, S., 2020. Beta-Strang-Ausbildung eines Faltungsintermediates von BamA: Adsorption an Lipidmembranen induziert lokale Sekundärstruktur in Beta-Strang 9, 1. Aufl. Springer Spektrum, Wiesbaden. https://doi.org/https://doi.org/10.1007/978-3-658-29029-0_1
2019	Kleinschmidt, J.H., 2019. Correction To: Lipid-Protein Interactions. Lipid-Protein Interactions 2003, C1–C4. https://doi.org/10.1007/978-1-4939-9512-7_26
2019	Gerlach, L., Gholami, O., Schürmann, N., Kleinschmidt, J.H., 2019. Folding of β-Barrel Membrane Proteins into Lipid Membranes by Site-Directed Fluorescence Spectroscopy. Methods in Molecular Biology 2003, 465–492. https://doi.org/10.1007/978-1-4939-9512-7_20
2019	Schüßler, A., Herwig, S., Kleinschmidt, J.H., 2019. Kinetics of Insertion and Folding of Outer Membrane Proteins by Gel Electrophoresis. Methods in Molecular Biology 2003, 145–162. https://doi.org/10.1007/978-1-4939-9512-7_7
2019	Kleinschmidt, J.H., 2019. Lipid-Protein Interactions: Methods and Protocols, 682 Pages, 2nd ed. 2019. Springer, New York, NY, New York, NY. https://doi.org/10.1007/978-1-4939-9512-7
2018	Sharma, M., Kleinschmidt, J.H., 2018. Interactions of the Membrane Protein Chaperone Skp with BamD of the β-Barrel Assembly Machinery Complex from E. coli. Biophysical Journal 114, 243a–244a. https://doi.org/10.1016/j.bpj.2017.11.1356
2017	Knape, M., Ballez, M., Burghardt, N., Zimmermann, B., Bertinetti, D., Kornev, A.P., Herberg, F.W., 2017. Divalent metal ions control activity and inhibition of protein kinases. Metallomics 9, 1576–1584. https://doi.org/10.1039/c7mt00204a
2016	Gerlach, L., 2016. Einbau und Faltung von ß-Fass Membranproteinen in Bakterien, 1. Aufl. Springer Spektrum, Wiesbaden. https://doi.org/https://doi.org/10.1007/978-3-658-12654-4_3

Other Research Activities

from 01/2021	Mitglied der Studiengangsplanungskommission zur Reakkreditierung der Studiengänge Bachelor und Master Biologie Academic self-administration activity
03/2020	Design of a functional tryptophan and cysteine free mutant of BamA for spectroscopic studies on BAM-complex mediated folding and insertion of outer membrane proteins. Poster presentation
SS 2020	Rapid Development with Mentalab‘s Explore: Advanced Signal Processing in Sleep EEG Advising activity
03/2020	The integral membrane protein VDAC can form aqueous folding intermediates with beta-barrel-like structure in the absence of detergent micelles or lipid bilayers. Poster presentation
10/2019	Interactions of the periplasmic chaperone Skp with subunits of the β-barrel assembly machinery complex from Escherichia coli Presentation
02/2018	Interactions of the membrane protein chaperone Skp with BamD of the β-barrel assembly machinery complex from Escherichia coli Poster presentation
WS 2017/2018	Die Adsorption von entfaltetem β-Barrel Assembly Machinery Protein A (BamA) an Lipidmembranen führt in β-Strang neun zur Ausbildung nativer Sekundärstruktur Advising activity
02/2016	Folding and stability of integral membrane proteins in amphipols Presentation
from 08/2014	Kontaktperson der Gesellschaft für Biochemie und Molekularbiologie (GBM) an der Universität Kassel Academic self-administration activity
from 09/2013	Vorsitzender des Prüfungsausschusses des Studiengangs M.Sc. Biologie Academic self-administration activity

Subordinate Organisational Units

Universität Kassel, FB 10, FG Biophysik