Roland Klassen - Forschungsinformationssystem | Universität Kassel

Dr. Roland Klassen

Forschungsfelder

Mathematik, Naturwissenschaften

Forschungsinteressen

Hefegenetik, non-conventional yeasts, Ribotoxine, tRNA Modifikation, tRNA Reparatur, DNA Reparatur, Mutagenese, DNA Polymerasen, Antimykotika

Akademischer Werdegang

10.1994-03.2000 Studium der Biologie (WWU Münster)

04.2000-10.2004 Promotion im Fachbereich Mikrobiologie (WWU Münster)

Projektleitung

12/2015 - 11/2018

Funktionsüberlappung unter Modifikationen an der tRNA Antikodon-Schleife (tRNA Mods I)

Publikationen

5 von 5

2007	Paluszynski, J., Klassen, R., Meinhardt, F., 2007. Pichia acaciae killer system: Genetic analysis of toxin immunity. Applied and Environmental Microbiology 73, 4373–4378.
2006	Klassen, R., Jablonowski, D., Stark, M., Schaffrath, R., Meinhardt, F., 2006. Mating-type locus control of killer toxins from Kluyveromyces lactis and Pichia acaciae. FEMS Yeast Research 6, 404–413. https://doi.org/10.1111/j.1567-1364.2005.00006.x
2006	Paluszynski, J., Klassen, R., Rohe, M., Meinhardt, F., 2006. Various cytosine/adenine permease homologues are involved in the toxicity of 5-fluorocytosine in Saccharomyces cerevisiae. Yeast 23, 707–715.
2005	Klassen, R., Meinhardt, F., 2005. Induction of DNA damage and apoptosis in Saccharomyces cerevisiae by a yeast killer toxin. Cellular Microbiology 7, 393–401.
2004	Klassen, R., Teichert, S., Meinhardt, F., 2004. Novel yeast killer toxins provoke S-phase arrest and DNA damage checkpoint activation. Molecular Microbiology 53, 263–273.
2003	Klassen, R., Meinhardt, F., 2003. Structural and functional analysis of the killer element pPin1-3 from Pichia inositovora. Molecular Genetics and Genomics 270, 190–199. https://doi.org/10.1007/s00438-003-0920-5
2002	Klassen, R., Jablonowski, D., Schaffrath, R., Meinhardt, F., 2002. Genome organization of the linear Pichia etchellsii plasmid pPE1A: evidence for expression of an extracellular chitin-binding protein homologous to the alpha-subunit of the Kluyveromyces lactis killer toxin. Plasmid 47, 224–233. https://doi.org/10.1016/S0147-619X(02)00014-8
2002	Klassen, R., Meinhardt, F., 2002. Linear plasmids pWR1A and pWR1B of the yeast Wingea robertsiae are associated with a killer phenotype. Plasmid 48, 142–148.
2001	Klassen, R., Tontsidou, L., Larsen, M., Meinhardt, F., 2001. Genome organization of the linear cytoplasmic element pPE1B from Pichia etchellsii. Yeast 18, 953–961.
2001	Jablonowski, D., Fichtner, L., Martin, V.J., Klassen, R., Meinhardt, F., Stark, M., Schaffrath, R., Martin, V., 2001. Saccharomyces cerevisiae cell wall chitin, the Kluyveromyces lactis zymocin receptor. Yeast 18, 1285–1299. https://doi.org/10.1002/yea.776

Weitere Forschungsaktivitäten

2009	Post-Doc/Research Scientist I Auslandsaufenthalt
0	Additive actions of 5-fluorocytosine and fluconazole in resistant yeast strains Posterbeitrag
0	Additive actions of 5-fluorocytosine and fluconazole in resistant yeast strains Posterbeitrag
0	DNA repair pathways contribute to resistance against translational inhibitors in yeast Posterbeitrag
0	Evidence for additional permeases involved in the toxicity of the antifungal agent 5-fluorocytosine (5-FC) in Saccharomyces cerevisiae Posterbeitrag
0	Killer toxins of Kluyveromyces lactis and Pichia acaciae: mating inhibition and mating type control Posterbeitrag
0	Microbial linear plasmids. Microbiology Monographs, Vol. 7 (2007). Springer Verlag, Berlin Heidelberg Herausgebertätigkeit
0	Novel yeast killer toxins mediate cell cycle arrest during S-phase and activation of the DNA damage checkpoint kinase Rad53 Posterbeitrag
0	The killer element pPin1-3 of the yeast Pichia inositovora. Poster Posterbeitrag
0	The Pichia acaciae killer system: Genetic analysis of toxin immunity Posterbeitrag