Dr. Daniela Bertinetti
Research Interest
F&E, (Protein)Biochemie, zyklische Nukleotide, Biomolekulare Interaktionsanalyse, Fluoreszenzpolarisation, Biosensoren basierend auf Oberflächenplasmonresonanz-Technologie
Work Experience
01/2014 | Strahlenschutzbevollmächtigte und Leiterin des Zentralen Isotopenlabors der Universität Kassel
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07/2007 | Wissenschaftliche Mitarbeiterin an der Universität Kassel, Fachgebiet Biochemie, FB 10
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Academic background
01/2014 - heute
Universität Kassel
Strahlenschutzbevollmächtigte der Universität Kassel
Leiterin des Zentralen Isotopenlabors der Universität Kassel
05/2003- heute
Universität Kassel, Abtlg. Biochemie
wissenschaftliche Mitarbeiter: Postdoc
11/2009 - 05/2011
Universität Kassel, UniKassel Transfer
Technologiescout für den FB Naturwissenschaften
08/2007 - 10/2009
Universität Kassel, Abtlg. Biochemie
wissenschaftliche Mitarbeiter: Postdoc
07/2003 - 06/2007
Universität Kassel, Abtlg. Biochemie
wissenschaftliche Mitarbeiter: Doktorand Projects as Co-Investigator
Publications
2022 | Happ, J.T., Arveseth, C.D., Bruystens, J., Bertinetti, D., Nelson, I.B., Olivieri, C., Zhang, J., Hedeen, D.S., Zhu, J.-F., Capener, J.L., Bröckel, J.W., Vu, L., King, C.C., Ruiz-Perez, V., Ge, X., Veglia, G., Herberg, F.W., Taylor, S.S., Myers, B.R., 2022. A PKA inhibitor motif within SMOOTHENED controls Hedgehog signal transduction. Nature Structural & Molecular Biology 29, 990–999. https://doi.org/10.1038/s41594-022-00838-z |
2021 | Lasonder, E., More, K., Singh, S., Haidar, M., Bertinetti, D., Kennedy, E.J., Herberg, F.W., Holder, A.A., Langsley, G., Chitnis, C.E., 2021. cAMP-Dependent Signaling Pathways as Potential Targets for Inhibition of Plasmodium falciparum Blood Stages. Frontiers in Microbiology 12, 1–15. https://doi.org/10.3389/fmicb.2021.684005 |
2021 | Reginka, M., Hoang, H., Efendi, Ö., Merkel, M., Huhnstock, R., Holzinger, D., Dingel, K., Sick, B., Bertinetti, D., Herberg, F.W., Ehresmann, A., 2021. Transport efficiency of biofunctionalized magnetic particles tailored by surfactant concentration. Langmuir 37, 8498–8507. https://doi.org/10.1021/acs.langmuir.1c00900 |
2020 | Manschwetus, J.T., Wallbott, M., Fachinger, A., Obergruber, C., Pautz, S., Bertinetti, D., Schmidt, S.H., Herberg, F.W., 2020. Binding of the Human 14-3-3 Isoforms to Distinct Sites in the Leucine-Rich Repeat Kinase 2. Frontiers in Neuroscience 14, 302. https://doi.org/10.3389/fnins.2020.00302 |
2020 | Palencia-Campos, A., Aoto, P., Machal, E.M.F., Rivera-Barahona, A., Soto-Bielicka, P., Bertinetti, D., Baker, B., Vu, L., Piceci-Sparascio, F., Torrente, I., Boudin, E., Peeters, S., van Helden, W., Huber, C., Bonneau, D., Hildebrand, M.S., Coleman, M., Bahlo, M., Bennett, M., Schneider, A., Scheffer, I., Kibæk, M., Kristiansen, B.S., Issa, M.Y., Mehrez, M., Ismail, S., Tenorio, J., Li, G., Skålhegg, B., Otaify, G., Temtamy, S., Aglan, M., Jønch, A.E., Luca, A., Mortier, G., Cormier-Daire, V., Ziegler, A., Wallis, M., Herberg, F.W., Lapunzina, P., Taylor, S.S., Ruiz-Perez, V.L., 2020. Germline and Mosaic Variants in PRKACA and PRKACB Cause a Multiple Congenital Malformation Syndrome. American Journal of Human Genetics 107, 977–988. https://doi.org/10.1016/j.ajhg.2020.09.005 |
2020 | Knape, M., Wallbott, M., Burghardt, N.G., Bertinetti, D., Hornung, J., Schmidt, S., Lorenz, R., Herberg, F.W., 2020. Molecular Basis for Ser/Thr Specificity in PKA Signaling. Cells 9, 1548. https://doi.org/10.3390/cells9061548 |
2019 | Lelle, M., Otte, M., Thon, S., Bertinetti, D., Herberg, F.W., Benndorf, K., 2019. Chemical synthesis and biological activity of novel brominated 7-deazaadenosine-3’,5’-cyclic monophosphate derivatives. Bioorganic & medicinal chemistry 27, 1704–1713. https://doi.org/10.1016/j.bmc.2019.03.024 |
2018 | Bendzunas, N.G., Dörfler, S., Autenrieth, K., Bertinetti, D., Machal, E.M.F., Kennedy, E.J., Herberg, F.W., 2018. Investigating PKA-RII specificity using analogs of the PKA:AKAP peptide inhibitor STAD-2. Bioorganic & medicinal chemistry 26, 1174–1178. https://doi.org/10.1016/j.bmc.2018.02.001 |
2018 | Vighi, E., Rentsch, A., Henning, P., Comitato, A., Hoffmann, D., Bertinetti, D., Bertolotti, E., Schwede, F., Herberg, F.W., Genieser, H.-G., Marigo, V., 2018. New cGMP analogues restrain proliferation and migration of melanoma cells. OncoTarget 9, 5301–5320. https://doi.org/10.18632/oncotarget.23685 |
2018 | Kailing, L.L., Bertinetti, D., Paul, C.E., Manszewski, T., Jaskolski, M., Herberg, F.W., Pavlidis, I.V., 2018. S-Adenosyl-L-Homocysteine Hydrolase Inhibition by a Synthetic Nicotinamide Cofactor Biomimetic. Frontiers in Microbiology 9, 505. https://doi.org/10.3389/fmicb.2018.00505 |
