Aufsatz in einer Fachzeitschrift
Dynamic mechanical characterization of poly(glycerol sebacate)/poly (butylene succinate-butylene dilinoleate) blends for cardiac tissue engineering by flat punch nanoindentation
Details zur Publikation
Autor(inn)en: | Merle, B.; Kraus, X.; Tallawi, M.; Scharfe, B.; El Fray, M.; Aifantis, K.; Boccaccini, A.; Göken, M. |
Verlag: | ELSEVIER SCIENCE BV |
Publikationsjahr: | 2018 |
Zeitschrift: | Materials Letters |
Seitenbereich: | 115-118 |
Jahrgang/Band : | 221 |
Erste Seite: | 115 |
Letzte Seite: | 118 |
Seitenumfang: | 4 |
ISSN: | 0167-577X |
eISSN: | 1873-4979 |
DOI-Link der Erstveröffentlichung: |
Zusammenfassung, Abstract
The viscoelastic properties of polymer blends of poly(glycerol sebacate) (PGS) and poly(butylene succinate-dilinoleate) (PBS-DLA) copolymer intended for cardiac tissue patches are investigated by dynamic flat punch nanoindentation at frequencies ranging from 1 to 45 Hz. The storage modulus is found to depend weakly on the testing frequency, the lowest value being for 1 Hz, which corresponds to the usual heart rate. More significantly, it is found that varying the PGS content between 40 and 70 wt% allows tuning the storage modulus of the blends between 11 and 39 MPa. The reliability of the nanoindentation method is validated by reference dynamic mechanical measurements on thicker PBS-DLA samples using a tensile testing machine. (C) 2018 Elsevier B.V. All rights reserved.
The viscoelastic properties of polymer blends of poly(glycerol sebacate) (PGS) and poly(butylene succinate-dilinoleate) (PBS-DLA) copolymer intended for cardiac tissue patches are investigated by dynamic flat punch nanoindentation at frequencies ranging from 1 to 45 Hz. The storage modulus is found to depend weakly on the testing frequency, the lowest value being for 1 Hz, which corresponds to the usual heart rate. More significantly, it is found that varying the PGS content between 40 and 70 wt% allows tuning the storage modulus of the blends between 11 and 39 MPa. The reliability of the nanoindentation method is validated by reference dynamic mechanical measurements on thicker PBS-DLA samples using a tensile testing machine. (C) 2018 Elsevier B.V. All rights reserved.
Schlagwörter
Cardiac tissue engineering, Dynamic mechanical analysis, Nanoindentation
