Journal article
Dynamic mechanical characterization of poly(glycerol sebacate)/poly (butylene succinate-butylene dilinoleate) blends for cardiac tissue engineering by flat punch nanoindentation
Publication Details
Authors: | Merle, B.; Kraus, X.; Tallawi, M.; Scharfe, B.; El Fray, M.; Aifantis, K.; Boccaccini, A.; Göken, M. |
Publisher: | ELSEVIER SCIENCE BV |
Publication year: | 2018 |
Journal: | Materials Letters |
Pages range : | 115-118 |
Volume number: | 221 |
Start page: | 115 |
End page: | 118 |
Number of pages: | 4 |
ISSN: | 0167-577X |
eISSN: | 1873-4979 |
DOI-Link der Erstveröffentlichung: |
Abstract
The viscoelastic properties of polymer blends of poly(glycerol sebacate) (PGS) and poly(butylene succinate-dilinoleate) (PBS-DLA) copolymer intended for cardiac tissue patches are investigated by dynamic flat punch nanoindentation at frequencies ranging from 1 to 45 Hz. The storage modulus is found to depend weakly on the testing frequency, the lowest value being for 1 Hz, which corresponds to the usual heart rate. More significantly, it is found that varying the PGS content between 40 and 70 wt% allows tuning the storage modulus of the blends between 11 and 39 MPa. The reliability of the nanoindentation method is validated by reference dynamic mechanical measurements on thicker PBS-DLA samples using a tensile testing machine. (C) 2018 Elsevier B.V. All rights reserved.
The viscoelastic properties of polymer blends of poly(glycerol sebacate) (PGS) and poly(butylene succinate-dilinoleate) (PBS-DLA) copolymer intended for cardiac tissue patches are investigated by dynamic flat punch nanoindentation at frequencies ranging from 1 to 45 Hz. The storage modulus is found to depend weakly on the testing frequency, the lowest value being for 1 Hz, which corresponds to the usual heart rate. More significantly, it is found that varying the PGS content between 40 and 70 wt% allows tuning the storage modulus of the blends between 11 and 39 MPa. The reliability of the nanoindentation method is validated by reference dynamic mechanical measurements on thicker PBS-DLA samples using a tensile testing machine. (C) 2018 Elsevier B.V. All rights reserved.
Keywords
Cardiac tissue engineering, Dynamic mechanical analysis, Nanoindentation
